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Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action


Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics, biodistribution, bioavailability, local concentration, and clearance of drug substances for the treatment of human disease, most notably cancer. Written by a team of international experts, this book examines the use of quantitative imaging techniques in designing and evaluating novel drug delivery systems and applications. Drug Delivery Applications of Noninvasive Imaging offers a full arsenal of tested and proven methods, practices and guidance, enabling readers to overcome the many challenges in creating successful new drug delivery systems. The book begins with an introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitative analysis Imaging drugs and drug carriers at the site of action, including low-molecular weight radiopharmaceuticals, peptides and proteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routes other than intravenous injection, such as pulmonary and oral delivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drug development and drug delivery Chapters are based on a thorough review of the current literature as well as the authors' firsthand experience working with imaging techniques for the development of novel drug delivery systems. Presenting state-of-the-technology applications of imaging in preclinical and clinical evaluation of drug delivery systems, Drug Delivery Applications of Noninvasive Imaging offers cost-effective strategies to pharmaceutical researchers and students for developing drug delivery systems that accurately target a broad range of disease conditions.

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Pathak Yashwant Antibody-Mediated Drug Delivery Systems. Concepts, Technology, and Applications


This book covers various aspects of antibody mediated drug delivery systems – theoretical aspects, processing, viral and non-viral vectors, and fields where these systems find and /or are being evaluated for applications as therapeutics and diagnostic treatment. Chapters discuss actual applications of techniques used for formulation and characterization. Applications areas include cancer, pulmonary, ocular diseases; brain drug delivery; and vaccine delivery. The contributing authors represent over 10 different countries, covering recent developments happening around the globe.

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Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery


Steroid dimers are an important group of compounds produced by various marine organisms, and also synthesized in the laboratories. This group of compounds possesses various pharmacological and biological properties, and can also be used to create “molecular umbrellas” for drug delivery. Steroid Dimers: Chemistry and Applications in Drug Design and Delivery provides an up-to-date overview on the chemistry and applications of steroid dimers of natural and synthetic origins. The book includes easy-to-follow synthetic protocols for various classes of important dimeric steroids, source details, valuable spectroscopic data and depiction of unique structural features of natural steroidal dimers, and the Structure-Activity-Relationships (SARs) of some pharmacologically active dimeric steroids. Topics covered include: introduction to steroid dimers synthesis and chemistry of noncyclic and cyclic steroid dimers naturally occurring steroid dimers – cephalostatins, ritterazines and crellastatins biological and pharmacological functions of steroid dimers and their application in drug design and discovery steroid dimers as “molecular umbrellas” for drug delivery Steroid Dimers: Chemistry and Applications in Drug Design and Delivery is an essential guide to this important class of natural and synthetic compounds for researchers and students of natural products chemistry and biochemistry, synthetic organic and medicinal chemistry, and drug design, discovery and delivery.

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Rebecca A. Bader Engineering Polymer Systems for Improved Drug Delivery


Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

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Tomalia Donald A. Dendrimer-Based Drug Delivery Systems. From Theory to Practice


The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.

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Susheel Kalia Biodegradable and Biobased Polymers for Environmental and Biomedical Applications


This volume incorporates 13 contributions from renowned experts from the relevant research fields that are related biodegradable and biobased polymers and their environmental and biomedical applications. Specifically, the book highlights: Developments in polyhydroxyalkanoates applications in agriculture, biodegradable packaging material and biomedical field like drug delivery systems, implants, tissue engineering and scaffolds The synthesis and elaboration of cellulose microfibrils from sisal fibres for high performance engineering applications in various sectors such as the automotive and aerospace industries, or for building and construction The different classes and chemical modifications of tannins Electro-activity and applications of Jatropha latex and seed The synthesis, properties and applications of poly(lactic acid) The synthesis, processing and properties of poly(butylene succinate), its copolymers, composites and nanocomposites The different routes for preparation polymers from vegetable oil and the effects of reinforcement and nano-reinforcement on the physical properties of such biobased polymers The different types of modified drug delivery systems together with the concept of the drug delivery matrix for controlled release of drugs and for antitumor drugs The use of nanocellulose as sustainable adsorbents for the removal of water pollutants mainly heavy metal ions, organic molecules, dyes, oil and CO2 The main extraction techniques, structure, properties and different chemical modifications of lignins Proteins and nucleic acids based biopolymers The role of tamarind seed polysaccharide-based multiple-unit systems in sustained drug release

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Dionysios Douroumis Drug Delivery Strategies for Poorly Water-Soluble Drugs


Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials.

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Группа авторов Computational Pharmaceutics


Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

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Группа авторов Nanoparticulate Drug Delivery Systems


Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

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Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi


RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: Mechanisms, Barriers, and Analysis of RNAi Delivery Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective Bioconjugation of siRNA for Site Specifi c Delivery Nanoscale Delivery Systems for RNAi Environmentally-Responsive Delivery Systems for RNAi Light-sensitive RNAi Viral-Mediated Delivery of shRNA and miRNA RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease miRNA as therapeutic agents and targets Advanced Delivery and Therapeutic Applications of RNAi combines the essential aspects of developing RNAi therapeutics from bench to clinic, and is invaluable for researchers working on RNAi, drug discovery and delivery, biomedical engineering, biomaterials, molecular biology, and biotechnology.

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Chun Li Lab | MD Anderson Cancer Center

Research activities in the laboratory of Chun Li, Ph.D., are primarily focused on two areas: 1) the development of targeted imaging probes for noninvasive characterization of molecular events associated with tumor progression and regression and 2) the development of novel drug-delivery systems for selective delivery of diagnostic and therapeutic agents.

Chun Li | MD Anderson Cancer Center

Research activities in Dr. Chun Li’s laboratory are primarily focused on two areas: 1) the development of targeted imaging probes for noninvasive characterization of molecular events associated with tumor progression and regression and 2) the development of novel drug-delivery systems for selective delivery of diagnostic and therapeutic agents. Molecular imaging probes used in nuclear ...

Li-Chun Sun, PhD | Medicine

Drug Delivery, 11(4): 231-238, 2004. Sun LC, Vasilevich NI, Coy DH, et al. Abilities of 3,4-diarylfuran-2-one analogues of combretastatin A-4 to inhibit proliferation of tumor cell lines and growth of the relevant tumors in nude mice. Anticancer Research, 24(1): 179-186, 2004.

Drug Delivery: Vol 27, No 1 - Taylor & Francis

Publishes open access research on oral, pulmonary, nasal, parental and transdermal drug delivery systems and conjugates, and drug entry and targeting. Log in | Register Cart. Home All Journals Drug Delivery List of Issues Volume 27, Issue 1 2019 Impact Factor. 4.902 ...

Li Chun – Wikipedia

Li Chun (chinesisch 李純 / 李纯, Pinyin Lǐ Chún; * 11. Februar 1988 in Hunan, Volksrepublik China), in Japan auch besser bekannt als Junjun (ジュンジュン) war Mitglied der J-Pop-Girlgroup Morning Musume.Sie wurde am 15. März 2007 als Mitglied der 8. Generation angekündigt. Li Chun und Qian Lin sind in Morning Musume bisher die einzigen ausländischen Mitglieder, die je ...

Li Chun Timings For 2019 Are Out, Here's When To Deposit ...

Li Chun 2019 Falls On 4 Feb, Monday. Even as 2019 barely gets started, the hype train for Chinese New Year has already begun. And before CNY comes the tradition of depositing money on Li Chun in an attempt to secure good luck for the year ahead.

Li Chun (actress) - Wikipedia

Li Chun (Chinese: 李纯; born 15 February 1988) is a Chinese actress, best known for her roles in television series as Ni Mantian and Wei Yanwan in The Journey of Flower (2015) and Ruyi's Royal Love in the Palace (2018) respectively, and has received critical acclaim for her film work, particularly as Qinhuainü in The Flowers of War and Lian Mei in Avalokitesvara

ROS-responsive capsules engineered from green tea ...

Reactive oxygen species (ROS)-responsive nanocapsules for cancer drug delivery were engineered from green tea polyphenol–metal networks. Briefly, DOX-doped ZIF-8 nanoparticles were synthesized via coprecipitation and coated with a layer of EGCG–Fe(iii) complexes by suspending in EGCG and ferric chloride aque

Advanced Drug Delivery Reviews - Journal - Elsevier

The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery.

Carrageenan and its applications in drug delivery ...

Thus, CG-based vaginal drug delivery systems containing topical microbicides were suggested to treat sexually transmitted infections (Li, Zaveri et al., 2013). Similarly, pregelatinized starch gels containing various ratios of κ-CG could offer a wide range of bioadhesive strength, leading to improved physical properties and prolonged buccal delivery of miconazole ( Lefnaoui & Moulai-Mostefa ...

Li Chuan Food Products Pte Ltd

At Li Chuan Food Products, we are fully committed to meet the highest standard in food manufacturing process. We have achieved HACCP Certifications, Grade A AVA listing, Halal Certifications, EU Licenses, US Food and Drug Administration listing and bizSafe Level 3 Certification by MOM. In our efforts to continuously improve, we constantly seek and adopt the best food manufacturing practices ...

Chun-Li - Wikipedia

Chun-Li (春麗, also チュン ... She encounters Ryu, who has fallen from grace and had hired himself out as a bodyguard to drug smugglers, and winds up befriending him and Birdie as well as Ken, also rescuing Cammy from being captured by Sodom. Shadaloo is once again responsible for the death of her father, though the exact identity of the killer is not revealed. In Malibu Comics' short ...

Advanced Drug Delivery Reviews | Journal | ScienceDirect ...

Drug delivery progress in benign and malignant lesions of aging skin. Edited by Tarl W. Prow, Anna Mandinova. 1 January 2020. Editor's Collection 2019. Edited by Hamidreza Ghandehari. November–December 2019. Sequential Drug/Gene Delivery in Tissue Engineering & Regenerative Medicine. Edited by Sing Yian Chew. September–October 2019. Nanotechnology Enabled Regenerative Medicine for ...

Mesoporous silica nanoparticles: synthesis ...

With their tailored mesoporous structure and high surface area, MSNs as drug delivery systems (DDSs) show significant advantages over traditional drug nanoca … Mesoporous silica nanoparticles: synthesis, biocompatibility and drug delivery Adv Mater. 2012 Mar 22;24(12):1504-34. doi: 10.1002/adma.201104763. Epub 2012 Feb 29. Authors Fangqiong Tang 1 , Linlin Li, Dong Chen. Affiliation 1 ...

Summoners War Monster List Guide – Rune Recommendations ...

Welcome to the monster list! This page will be updated frequently to include all the monsters in the game! Each tab lists the different element monsters. If you cannot find a specific monster, use th

Li Chun 2019 (4 Feb) – When is the Best Date & Time to ...

Li Chun is a date on the Chinese calendar that signifies the beginning of spring. This date often falls around Chinese New Year, although the date of CNY can actually be before or after Li Chun. This year, Li Chun falls on 4 Feb 2019. That happens to be the day before Chinese New Year on 5 Feb 2019, but that’s a coincidence.

Chun Dr. Li - Professor and Director, The John S. Dunn ...

View Chun Dr. Li’s profile on LinkedIn, the world's largest professional community. Chun has 2 jobs listed on their profile. See the complete profile on LinkedIn and discover Chun’s ...

Home Page ::: Current Drug Delivery

Current Drug Delivery aims to publish peer-reviewed articles, research articles, in-depth reviews/mini-reviews, and drug clinical trials studies in the rapidly developing field of drug delivery. Modern drug research aims to build delivery properties of a drug at the design phase, however in many cases this idea cannot be met and the development of delivery systems becomes as important as the ...

Nanotecnologia Drug Delivery Markt Taglia Forschung by ...

La relazione d’esame comprende i dati chiave del mercato identificati con le dimensioni attuali del mercato, la quota, le aree chiave di performance, i marchi guida presenti nello spazio di mercato Nanotecnologia Drug Delivery. Le indagini condotte in questo rapporto sono condotte sia a livello di area sia a livello mondiale. In questo modo, il rapporto è utile per i periti che sperano di ...

Research Projects — Fachgruppe Pharmazie

Enhanced drug delivery into the deep lung; Particle engineering approaches based on spray drying and spray freeze drying techniques are tested for a more efficient lung deposition of drugs, including SME as well as protein drugs Drug delivery to the blood-brain-barrier With the help of newly developed ex-vivo tissue model we aim for understanding drug transport mechanisms at the BBB and the ...

About Dr. Shyh-Dar Li | Laboratory of Targeted Drug ...

Dr. Shyh-Dar Li, BSc(Pharm), PhD Angiotech Professor in Drug Delivery Profile Dr. Shyh-Dar Li received a BSc in Pharmacy from National Taiwan University and a PhD in Pharmaceutical Sciences from University of North Carolina at Chapel Hill. After completing his postdoctoral training at University of California, San Diego, he joined Ontario Institute […]

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer ...

The delivery of the known anticancer drug doxorubicin into tumors by self-assembled DNA origami nanostructures was performed, and this approach showed prominent therapeutic efficacy in vivo. The DNA origami carriers were prepared through the self-assembly of M13mp18 phage DNA and hundreds of complementary DNA helper strands; the doxorubicin was subsequently noncovalently intercalated into ...

Cancer drug delivery in the nano era: An overview and ...

Hough B, Posner M, Chung C, et al: A phase II study of single agent OSI-7904L in patients with metastatic or recurrent squamous cell carcinoma of the head and neck (SCCHN). Journal. 27:e170052009. 181 Pattni BS, Chupin VV and Torchilin VP: New developments in liposomal drug delivery. Chem Rev. 115:10938–10966. 2015. View Article: Google Scholar: PubMed/NCBI. 182 Semple SC, Leone R, Wang J ...

Dr Chun Xu - UQ Researchers

Xu, Chun, He, Yan, Li, Zhihao, Ahmad Nor, Yusilawati and Ye, Qingsong (2018). Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms. Journal of Materials Chemistry B, 6 (13), 1899-1902. doi: 10.1039/c7tb03201c

Associate Professor Chunxia Zhao - UQ Researchers

Development of core‐shell nanoparticle drug delivery systems based on biomimetic mineralization. Yang, Guangze, Liu, Yun, Jin, Song and Zhao, Chun‐Xia (2020). Development of core‐shell nanoparticle drug delivery systems based on biomimetic mineralization. ChemBioChem, 21 (20) cbic.202000105, 2871-2879. doi: 10.1002/cbic.202000105

Yan-Chun LI | Lecturer | Dr. | Jilin University, Changchun ...

Yan-Chun Li [...] Zhihong Nie ... drug delivery, and solar cells. How to manipulate the formation and stability of these structures is a key facter for application in the field of block copolym ...

Carbon Nanotubes Protect DNA Strands during Cellular Delivery

Chun-Hua Lu, Chun-Ling Zhu, Juan Li, Jing-Jing Liu, Xi Chen, Huang-Hao Yang. Using graphene to protect DNA from cleavage during cellular delivery. Chemical Communications 2010 , 46 (18) , 3116.

Chun Li - Greater Boston Area | Professional Profile ...

View Chun Li’s profile on LinkedIn, the world's largest professional community. Chun has 7 jobs listed on their profile. See the complete profile on LinkedIn and discover Chun’s connections ...

NICM HRI | Chun Guang Li

Chun Guang Li. PhD Executive Committee Member, NICM Health Research Institute Professor of Pharmacology Research, NICM Health Research Institute . Professor Li commenced his current full-time role as Pharmacology leader at NICM in late 2012. In the previous five years he worked as a full time academic in the School of Health Sciences at RMIT University where he held the position of Director of ...

Mesoporous Silica Nanoparticles: Synthesis ...

Chunbo Yang, Zhengzheng Shi, Cong Feng, Rui Li, Sihao Luo, Xiangfeng Li, Liping Ruan, An Adjustable pH‐Responsive Drug Delivery System Based on Self‐Assembly Polypeptide‐Modified Mesoporous Silica, Macromolecular Bioscience, 10.1002/mabi.202000034, 20, 6, (2020).

Delivery de Chun-li Chinese Food - Itaim, Sao Paulo ...

Faça seu pedido online no Chun-li Chinese Food - Itaim, delivery de Comida Chinesa em Sao Paulo aqui no iFood. Acesse e peça já!

Li Chun | Sonicstory Wiki | Fandom

Li Chun war eine Meisterin der Dunklen Meister des Ninjutsu. In Wirklichkeit hieß sie Cassan-Dra the Echidna und arbeitete bei der Dark Legion. Li Chun wollte fliehen, doch Conquering Storm stach sie mit ihrem Katana ab. Li Chun war sehr aggressiv und sehr loyal zu der Dark Legion. Sie war auch sehr schnell genervt, was ihre Schwachstelle war. Li Chun wusste, wie gefährlich die Dunklen ...

华南理工大学教师信息 - scut.edu.cn

36. Yang Li, Feng Wang, Tian-Meng Sun, Jin-Zhi Du, Jun Wang*, Surface-Modulated and Thermoresponsive Polyphosphoester Nanoparticles for Enhanced Intracellular Drug Delivery, Sci. China Chem. 2014, 57, 579–585. 37. You-Yong Yuan, Chen-Qiong Mao, Xiao-Jiao Du, Jin-Zhi Du, Feng Wang, Jun Wang*, Surface Charge Switchable Nanoparticles Based on ...

Laboratory for Drug Delivery - Members

Yeu Chun Kim, PhD 2007, “Transdermal Drug Delivery Enhanced by Magainin Peptide” Joshua Hutcheson, MS 2008, “Quantification and Control of Ultrasound-Mediated Cell Death Modes” Sean Sullivan , PhD May 2009, "Polymer Microneedles for Transdermal Delivery of Biopharmaceuticals"

Chun LI | Distinguished Professor | PhD | Tsinghua ...

Chun Li Glycyrrhetinic acid 3-O-mono-β-d-glucuronide (GAMG), an important pharmaceutical intermediate and functional sweetener, has broad applications in the food and medical industries.

Chun Li Black Gothic Jacket | Goth Jacket - Gothic Babe Co

Description: Chun Li Black Gothic Jacket cuz nothing will stand in your way. You kickass in this casual long sleeve jacket featuring a faux fur turtle neck collar and sleeves with stylish closure type buttons. Specifications: Material: CottonClothing Length: RegularCollar: TurtleneckSleeve Style: RegularSleeve Length: FullClosure Type: Single ...

Clinical Characteristics of Coronavirus Disease 2019 in ...

Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of...

The Application of Thermosensitive Nanocarriers in ...

Environmental drug delivery system responding to different conditions, such as temperature, pH, magnetic field, electric field, ultrasound, and so forth, has gained a great attention for controlled drug delivery [15–19].Temperature is a typical example of “triggers” at the diseased site that could be exploited with nanocarriers.

Nicki Minaj - Chun Li (Lyric Video) HD - YouTube

***Disclaimer: This is not the official lyric video. All rights goes to its rightful owner/owners. No copyright infringement intended. © Copyright Disclaimer...

Mecozzi Sandro Thermodynamics of Pharmaceutical Systems. An introduction to Theory and Applications


Designed for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems. Students and practitioners involved in drug discovery, drug delivery, and drug action will benefit from Connors' and Mecozzi's authoritative treatment of the fundamentals of thermodynamics as well as their attention to drug molecules and experimental considerations. They will appreciate, as well, the significant revisions to the Second Edition. Expanding the book's scope and usefulness, the new edition: Explores in greater depth topics most relevant to the pharmacist such as drug discovery and drug delivery, supramolecular chemistry, molecular recognition, and nanotechnologies Moves the popular review of mathematics, formerly an appendix, to the front of the book Adds new textual material and figures in several places, most notably in the chapter treating noncovalent chemical interactions Two new appendices provide ancillary material that expands on certain matters bordering the subject of classical thermodynamics Thermodynamics need not be a mystery nor confined to the realm of mathematical theory. Thermodynamics of Pharmaceutical Systems, Second Edition demystifies for students the profound thermodynamic applications in the laboratory while also serving as a handy resource for practicing researchers.

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Группа авторов Chemical Aspects of Drug Delivery Systems

Группа авторов Novel Delivery Systems for Transdermal and Intradermal Drug Delivery


This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

12214 RUR

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Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering


Enables readers to apply process dynamics and control theory to solve bioprocess and drug delivery problems The control of biological and drug delivery systems is critical to the health of millions of people worldwide. As a result, researchers in systems biology and drug delivery rely on process dynamics and control theory to build our knowledge of cell behavior and to develop more effective therapeutics, controlled release devices, and drug administration protocols to manage disease. Written by a leading expert and educator in the field, this text helps readers develop a deep understanding of process dynamics and control theory in order to analyze and solve a broad range of problems in bioprocess and drug delivery systems. For example, readers will learn how stability criteria can be used to gain new insights into the regulation of biological pathways and lung mechanics. They'll also learn how the concept of a time constant is used to capture the dynamics of diffusive processes. Readers will also master such topics as external disturbances, transfer functions, and input/output models with the support of the author's clear explanations, as well as: Detailed examples from the biological sciences and novel drug delivery technologies 160 end-of-chapter problems with step-by-step solutions Demonstrations of how computational software such as MATLAB and Mathematica solve complex drug delivery problems Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering is written primarily for undergraduate chemical and biomedical engineering students; however, it is also recommended for students and researchers in pharmaceutical engineering, process control, and systems biology. All readers will gain a new perspective on process dynamics and control theory that will enable them to develop new and better technologies and therapeutics to treat human disease.

10145.25 RUR

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Группа авторов Biomedical Nanomaterials


The book discusses in a detailed manner various nanomaterials used for biomedical applications, including clinical applications, diagnosis and tissue engineering. After the presentation of an overview of biomedical nanomaterials, including their classification and applications, the first part of the book is devoted to biomedical nanomaterials for therapy applications. For example, polymer micelles, dendrimers, polymer-drug conjugates as well as antibody-drug conjugates are discussed with respect to their cancer drug delivery properties. The next parts discuss biomedical nanomaterials that are used for imaging, diagnosis and sensors, as well as for tissue engineering. In the final section, the safety of biomedical nanomaterials is elaborated.

15464.5 RUR

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Группа авторов Polyphosphazenes for Biomedical Applications


Brings together, analyzes, and contextualizes the latest findings and practical applications Polyphosphazenes, an emerging class of polymers, include macromolecules, which have been proven to be biocompatible, biodegradable, and bioactive. Their unprecedented structural diversity and unique properties make them suitable as vaccine adjuvants, microencapsulating agents, biodegradable materials, scaffolds for tissue engineering, biocompatible coatings, and carriers for gene delivery. Polyphosphazenes for Biomedical Applications offers a thorough review of polyphosphazene research findings in the life sciences, chemistry, and chemical engineering. It emphasizes biomedical applications as well as recent advances in polyphosphazene development such as high-throughput discovery and the latest controlled methods of synthesis. The book brings together, analyzes, and contextualizes a wealth of knowledge that previously could only be found scattered throughout the scientific literature. Following two introductory chapters, the book reviews: Vaccine delivery and immunomodulation Biomaterials Drug delivery systems Biodetection Well-defined polyphosphazenes: synthetic aspects and novel molecular architectures All the chapters have been written by leading researchers in the field. Editor Alexander Andrianov, who has led the effort to commercialize polyphosphazenes for biomedical applications, has carefully reviewed and edited all chapters to ensure readability, accuracy, and thoroughness. Polyphosphazenes for Biomedical Applications is not only intended for researchers working in polyphosphazene chemistry, but also for all researchers seeking solutions to problems arising in the areas of biomaterials, drug delivery systems, and controlled release formulations.

15819.1 RUR

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Dennis Douroumis Hot-Melt Extrusion. Pharmaceutical Applications


Hot-melt extrusion (HME) – melting a substance and forcing it through an orifice under controlled conditions to form a new material – is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.

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Recent important discoveries and developments in nanotechnology have had a remarkable and ever-increasing impact on many industries, especially materials science, pharmaceuticals, and biotechnology. Nanocarriers have been investigated for a wide variety of different medical applications. Some examples of these nanocarriers include polymersomes, liposomes, micelles and carbon-based nanomaterials. Within this book, the authors describe different features of carbon nanotubes (CNTs), survey the properties of both the multi-walled and single-walled varieties, and cover their applications in drug and gene delivery. In addition, the book explains the structure and properties of CNTs prepared by different method, and discussed their isolation and purification. The future of CNTs in the field of biomedical science will depend on minimizing their adverse effects by careful study of their structure and properties.

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